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Putting research into practice
PATIENTS UNDERGOING procedures at my facility’s cardiac electrophysiology (EP) lab typically receive I.V. procedural sedation with fentanyl (Sublimaze) and midazolam (Versed), which keep them sedated and comfortable throughout lengthy procedures. Unfortunately, in some patients these drugs also cause vomiting, which is particularly dangerous for a sedated patient. In addition, vomiting may trigger bleeding at vascular access sites.
Nurses in the EP la…

The Facts
In September 1999, a 52-year-old woman with a 15-year history of migraine went to the emergency department for migraine medication. The emergency department staff gave her nubain and 50 mg of Phenergan. Because the doses provided were higher than normal, the potentiating action of these drugs magnified the sedative effects. In the past, the pati…

Gastroparesis, a common event in persons with diabetes mellitus and functional dyspepsia, is defined as delayed gastric emptying. The major etiologic categories are diabetic, idiopathic, and postsurgical. The American Gastroenterological Association issued a medical position statement on the diagnosis and treatment of gastroparesis. The diagnosis is based on appropriate symptoms and signs of gastric dysmotility, delayed gastric emptying, and the absence of obstructing structural up…

A patient in the ED was supposed to receive Phenergan VC with codeine syrup (promethazine, phenylephrine, and codeine) to take at home to relieve coughing. When a nurse located a bottle of generic promethazine with codeine syrup and a large “C” around a “V” on the label, she mistakenly thought she’d identified promethazine VC with codeine syrup. In fact, this syrup didn’t conta…

Recent media reports have described bizarre episodes involving people who have taken Ambien–a popular prescription sleep aid–and awoken to find evidence that they ate a meal or took a drive around the neighborhood …

A PLAINTIFF’S VOLUNTARY CONSENT TO A NONSUIT AFTER SUMMARY JUDGMENT IS GRANTED FOR A DEFENDANT DOES NOT GIVE THE PLAINTIFF THE RIGHT TO REINSTITUTE A SUIT AGAINST THE SAME DEFENDANT. This should be evident. It is not!

Related Results

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Rep. Patrick Kennedy, son of Massachusetts Sen. Edward Kennedy, says he was disoriented from prescription medicines when he crashed his car into a security barrier near the Capitol early Thursday.
The Rhode Island congressman was not injured.
Kennedy, who has been open about his battles with substance abuse, said he had not be…

Baxter Healthcare Corp. has agreed to acquire a majority of ESI Lederle, a division of Wyeth, for $305 million. Baxter gains a 330,000 square foot facility at Cherry Hill, N.J., for manufacturing injectable small-volume drugs, and 1,000 new employees. Generic injectable products and patent-expired branded products under the deal include Phenergan (promethazine), Ativan …

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The most widely used antiemetic in the United States and probably the world, Phenergan (promethazine), is now black-boxed after 20 years of use CPhenergan Contraindicated Under Age 2,” April 2005, p. 9)?

I’ve used it an entire career in children 6 months and older without ever…

Byline: Todd Sloane
Over the years the Food and Drug Administration has been portrayed variously as sharing a corrupt bed with the industries it regulates, being notoriously inefficient or doing the best it can with limited resources and an overwhelming mandate. Never before, to my knowledge, has it been called infallible.
And yet that is the position staked out by the U.S. …