Pediatrics for Parents - Promethazine warning
The Food and Drug Administration (FDA) recently issued a warning concerning the use of promethazine in children younger than two years old. Promethazine is an antihistamine used to treat allergy symptoms such as watery and itchy eyes, and stuffy nose among others. It’s also used to treat nausea and motion sickness. The brand name is Phenergan, but there are many generic products that contain it.
Known side effects of this drug include drowsiness and respiratory suppression. Seven deaths and 22 cases of severe respiratory suppression in children under age two caused by this drug have been reported to the FDA. The FDA recommends not using promethazine in any form (syrups, tablets, suppositories, or injectable) in children under two years old.
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FDA Release, 4/06
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